Vitamin B12 deficiency: NICE guideline summary | The BMJ
Jun 13, 2024 · Vitamin B 12 deficiency is associated with a range of symptoms and signs, resulting in substantial variation in patient presentation. While epidemiological data are limited, cross sectional studies from the UK and US suggest a prevalence of 3% in people aged 20-39, increasing with age up to about 20% in people aged 85 and over.1 2 Complications of vitamin B 12 deficiency include visual changes ...
Covid-19: Two rare vaccine side effects detected in large ... - The BMJ
Feb 26, 2024 · The largest vaccine safety study to date has identified two new, but very rare, side effects associated with covid-19 vaccines—transverse myelitis and acute disseminated encephalomyelitis. The Global Vaccine Data Network cohort study included 99 million vaccinated people from 10 sites across eight countries. Researchers compared the observed with expected rate for 13 neurological, blood, and ...
Quality improvement into practice | The BMJ
Mar 31, 2020 · Definitions of quality improvement. Improvement in patient outcomes, system performance, and professional development that results from a combined, multidisciplinary approach in how change is delivered. 3. The delivery of healthcare with improved outcomes and lower cost through continuous redesigning of work processes and systems. 4.
Interpreting an isolated raised serum alkaline phosphatase level in …
Apr 3, 2013 · This article discusses the most common causes of raised alkaline phosphatase levels in an asymptomatic patient and provides advice on the relevant investigations. #### Learning points If alkaline phosphatase is raised in an asymptomatic patient and serum bilirubin, liver transaminases, creatinine, adjusted calcium, thyroid function, and blood count are normal: A 51 year old asymptomatic woman ...
Vaccinating against covid and flu at same time is safe, study shows
Oct 1, 2021 · Administering an influenza vaccine at the same time as a second dose of a covid-19 vaccine produced no safety concerns and preserves the immune response to both vaccines, say researchers.1 The results from the ComFluCOV study have already been presented to the UK Joint Committee on Vaccination and Immunisation and fed into the committee’s recent advice that the flu vaccine can be co ...
Distinguishing between type 1 and type 2 diabetes | The BMJ
Aug 11, 2020 · A random blood glucose test shows 14 mmol/L (250 mg/dL). Urinalysis is normal. The next day the patient returns, and a repeat fasting glucose test finds 14 mmol/L. This article is intended to help primary care doctors to differentiate between type 1 and type 2 diabetes when first diagnosing diabetes in a patient where the distinction is unclear.
Lucy Letby case: what happens now? | The BMJ
Oct 3, 2024 · A court judged nurse Lucy Letby guilty of seven murders and seven attempted murders in August 2023. But in the year since then questions have been raised about the evidence used to convict her. With a new statutory inquiry now sitting, Chris Stokel-Walker recaps what has happened with the case and what its wider implications are It was the most heinous of crimes. Nurse Lucy Letby was found ...
Which pain medications are effective for sciatica (radicular ... - The …
Oct 12, 2017 · What you need to know. The most effective pain medication to treat patients with sciatica or radicular leg pain is unclear. In approximately one third of patients, symptoms improve within two weeks; in three quarters of patients, symptoms improve within 12 weeks, but about a third of patients have persistent and disabling symptoms after one ...
Pathophysiology, diagnosis, and management of endometriosis
Nov 14, 2022 · Endometriosis affects approximately 190 million women and people assigned female at birth worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of endometrial-like tissue outside the uterus, which in many patients is associated with debilitating painful symptoms. Patients with endometriosis are also at greater risk of infertility, emergence of fatigue, multisite ...
Food and mood: how do diet and nutrition affect mental wellbeing?
Jun 29, 2020 · Poor nutrition may be a causal factor in the experience of low mood, and improving diet may help to protect not only the physical health but also the mental health of the population, say Joseph Firth and colleagues ### Key messages Depression and anxiety are the most common mental health conditions worldwide, making them a leading cause of disability.1 Even beyond diagnosed conditions ...