The 49ers are even more depleted at wide receiver in Week 3, placing greater emphasis on their star running back.

The Arizona Cardinals will face the San Francisco 49ers Sunday in Week 3. They kick off at 4:25 p.m. ET (1:25 p.m. Arizona ...

The Arizona Cardinals and San Francisco 49ers meet in Week 3 of the NFL season Sunday afternoon at Levi's Stadium.

The Arizona Cardinals and San Francisco 49ers meet in Week 3 of the NFL season Sunday afternoon at Levi's Stadium.

Preview the Week 3 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, betting lines and more.

The San Francisco 49ers are looking to rebound after an uneven 2024 season that saw the team finish 6-11 amidst a litany of injuries to key skill positions. The wide receiver group was decimated, but ...

All-white throwback jerseys are to serve as the 49ers’ heat shield if Sunday’s home opener with Arizona turns into another ...

The San Francisco 49ers are 2-0 and are favored to get to 3-0 against a division rival. Overall, things are good. However, if there is a problem, it is quite apparent to fans, media, and anyone who ...

San Francisco 49ers stars George Kittle and Fred Warner join Christian McCaffrey on the Saudi Arabia flag football team.

Next up for the Arizona Cardinals are the San Francisco 49ers. Both teams are 2-0 to start the season, although both teams have questions. The Niners have been devastated by injuries. Quarterback ...

Reports indicate that Juszczyk, who is 34 years old, cleared concussion protocol, according to Matt Barrows of The Athletic. Running back Christian McCaffrey and the 49ers can expect their star ...