The 49ers are even more depleted at wide receiver in Week 3, placing greater emphasis on their star running back.

The Arizona Cardinals will face the San Francisco 49ers Sunday in Week 3. They kick off at 4:25 p.m. ET (1:25 p.m. Arizona ...

McCaffrey is back at it after a lost 2024 season and another injury scare. "He looks like OPOY Christian," Trent Williams ...

San Francisco 49ers running back Christian McCaffrey caught a touchdown in the second quarter of Sunday's game against the ...

What a finish. The San Francisco 49ers defeat the Arizona Cardinals 16-15 on a walk-off field goal made by kicker Eddy Pineiro. Although the team and 49ers fans ...

The first play in the final quarter brought some controversy, as the 49ers believed they got a safety on Murray, who threw the ball away for intentional grounding near the goal line - though replay ...

Christian McCaffrey Mac Jones National Football League NFL - Arizona Cardinals vs. San Francisco 49ers - 09/21/2025 San Francisco 49ers ...

Recently signed kicker Eddy Pineiro made a 35-yard field goal on the final play to give the San Francisco 49ers a 16-15 win ...

Eddy Pineiro drilled a 35-yard field goal as time expired to lift the San Francisco 49ers to a 16-15 win over the Arizona Cardinals on Sunday afternoon in Santa Clara, Calif.

San Francisco 49ers star Christian McCaffrey missed practice Friday and was being listed as questionable for the team's Week ...

American football will now be played in Saudi Arabia, in the latest move by the Kingdom to corner the country's sports market ...

The Arizona Cardinals play the San Francisco 49ers Sunday afternoon in Week 3 for their first division game of the year, and after missing him in both games last season, they will have to deal with ...