The Arizona Cardinals and San Francisco 49ers meet in Week 3 of the NFL season Sunday afternoon at Levi's Stadium.

Mac Jones is expected to again start in place of Brock Purdy as the 49ers host the Arizona Cardinals on Sunday.

The San Francisco 49ers have had a tough time with the Arizona Cardinals since head coach Kyle Shanahan took over in the 2017 ...

ESPN’s Dan Graziano put a post together on the trade deadline and had the 49ers listed as a team that could make a move to ...

Expect Mac Jones to be behind center for the 49ers Sunday, and 49ers will look to break loose with running game.

The San Francisco 49ers have been leaning on Christian McCaffrey early in the season. The star running back has 17.5 rushes per game through two weeks and has added 8.5 targets per game. His total of ...

San Francisco 49ers stars George Kittle and Fred Warner join Christian McCaffrey on the Saudi Arabia flag football team.

The San Francisco 49ers are looking to rebound after an uneven 2024 season that saw the team finish 6-11 amidst a litany of injuries to key skill positions.

Next up for the Arizona Cardinals are the San Francisco 49ers. Both teams are 2-0 to start the season, although both teams have questions. The Niners have been devastated by injuries. Quarterback ...

Reports indicate that Juszczyk, who is 34 years old, cleared concussion protocol, according to Matt Barrows of The Athletic. Running back Christian McCaffrey and the 49ers can expect their star ...

Christian McCaffrey is averaging just 3.5 yards per carry this season -- a career low. And his longest run of the season has gained just 13 yards.

The Arizona Cardinals play the San Francisco 49ers Sunday afternoon in Week 3 for their first division game of the year, and after missing him in both games last season, they will have to deal with ...