The Arizona Cardinals take on the San Francisco 49ers Sunday in Week 3, kicking off at 4:25 p.m. ET (1:25 p.m. Arizona time) from Levi's Stadium in Santa Clara. It is the first of two matchups between ...

The Arizona Cardinals made their two standard practice squad elevations ahead of Week 3's road test against the San Francisco ...

The Cardinals are sixth in rushing yards allowed per game (78), 10th in yards per attempt allowed (3.8), and ninth in passer ...

Learn which TV channel or how to live stream the NFL Week 3 San Francisco 49ers and Arizona Cardinals game, Sunday, Sept. 21.

It's a big week for the Arizona Cardinals and quarterback Kyler Murray. Murray, who will look to guide Arizona to a 3-0 start to the season, are roa ...

San Francisco is a 2.5-point favorite in the latest Cardinals vs. 49ers odds from SportsLine consensus, while the over/under ...

Date: Sunday, Sept. 21 | Time: 4:25 p.m. ET Location: Levi's Stadium -- Santa Clara, California TV: Fox | Stream: NFL + Follow: CBS Sports App Odds: 49ers -3; O/U 43.5 (via DraftKings) ...

The San Francisco 49ers battle the Arizona Cardinals in their home opener at Levi’s Stadium on Sunday, Sept. 21 at 1:25 p.m.

The Cardinals announced Saturday that they elevated defensive lineman Anthony Goodlow and offensive lineman Jake Curhan from ...

Game prediction: Cardinals 23, 49ers 22. The Niners’ defense performs again, allowing only two touchdowns, but the San ...

The 49ers host the Cardinals in Week 3 on Sunday, September 21, 2025. With Brock Purdy unlikely to play, Mac Jones gets the start as San Francisco enters as a slight favorite. See odds, predictions, ...

Murray shined last season against the 49ers, starting on his second snap when he raced 50 yards for a touchdown and not ...