When Kyler Murray is at his best, he can be a nightmare for the opposition with his ability to break off long runs, avoid sacks and extend plays doing damage to even the best NFL defenses.

They announced Saturday that they elevated quarterback Adrian Martinez and receiver Malik Turner from the practice squad.

San Francisco 49ers wide receiver Jauan Jennings is questionable to suit up in Week 3 vs. the Arizona Cardinals. Here's the ...

Any time the Seahawks might have been tempted to feel too good about themselves in the wake of last Sunday’s win at Pittsburgh, all they had to do was think about one stat – 3-7.

Arizona comes into this game 2-0, but as a more flawed team than the one that swept San Francisco last year. The Cardinals' ...

Coach Kyle Shanahan said Friday that if 49ers wanted Purdy to be suited up as the emergency No. 3 quarterback, then Martinez, ...

San Francisco coach Kyle Shanahan said it’s “ highly unlikely ” Brock Purdy would return as the 49ers’ starting quarterback on Sunday, which means it’s highly likely Mac Jones will be under center for ...

A chance at becoming 3-0 is within reach for the San Francisco 49ers. All they have to do is duke it out with the Arizona Cardinals to get there. However, that' ...

The Arizona Cardinals made their two standard practice squad elevations ahead of Week 3's road test against the San Francisco ...

The San Francisco 49ers and Arizona Cardinals will meet on Sunday. Here's what fantasy owners should do with their 49ers in ...

Learn which TV channel or how to live stream the NFL Week 3 San Francisco 49ers and Arizona Cardinals game, Sunday, Sept. 21.