Learn which TV channel or how to live stream the NFL Week 3 San Francisco 49ers and Arizona Cardinals game, Sunday, Sept. 21.

Mac Jones is expected to again start in place of Brock Purdy as the 49ers host the Arizona Cardinals on Sunday.

San Francisco 49ers wide receiver Jauan Jennings is questionable to suit up in Week 3 vs. the Arizona Cardinals. Here's the latest on his injuries.

The San Francisco 49ers and Arizona Cardinals will meet on Sunday. Here's what fantasy owners should do with their 49ers in Week 3.

The Arizona Cardinals made their two standard practice squad elevations ahead of Week 3's road test against the San Francisco 49ers, and there might

The best VPNs for streaming are not free, but most do offer free-trials or money-back guarantees. By leveraging these offers, you can watch 49ers vs. Cardinals in the NFL without committing with your cash. This isn't a long-term solution, but it does give you enough time to live stream select fixtures from the NFL before recovering your investment.

Game prediction: Cardinals 23, 49ers 22. The Niners’ defense performs again, allowing only two touchdowns, but the San Francisco pass game sputters with only one viable receiver (Ricky Pearsall), and special teams miscues carry the day.

This game will be broadcast nationally on FOX television, though it's mostly limited to viewers around the west coast as the Dallas Cowboys vs Chicago Bears gets majority of the national stage. Adam Amin (play-by-play), Mark Sanchez (analyst) and Kristina Pink (sideline) will be featured on the broadcast.

The San Francisco 49ers battle the Arizona Cardinals in their home opener at Levi’s Stadium on Sunday, Sept. 21 at 1:25 p.m. PDT. The Niners are coming off consecutive road victories to open the season, including a 26-21 win in New Orleans with backup quarterback Mac Jones directing the offense.

Matt Maiocco details the 49ers' latest roster moves ahead of San Francisco's Week 3 matchup with the Arizona Cardinals on Sunday at Levi's Stadium.