The Sunday afternoon Cardinals vs. 49ers game will kick off at 4:25 p.m. ET on FOX. (Out-of-market fans can catch the game on ...

The San Francisco 49ers (2-0) host an NFC West showdown against the Arizona Cardinals (2-0) on Sunday, September 21, 2025 at ...

The Arizona Cardinals and San Francisco 49ers meet in Week 3 of the NFL season Sunday afternoon at Levi's Stadium.

Mac Jones is expected to again start in place of Brock Purdy as the 49ers host the Arizona Cardinals on Sunday.

Coach Kyle Shanahan said Friday that if 49ers wanted Purdy to be suited up as the emergency No. 3 quarterback, then Martinez, ...

The Arizona Cardinals have a chance at a 3-0 start when they head to San Francisco to take on the 49ers. It's their toughest ...

The Arizona Cardinals completed their week of practice on Friday for Sunday’s game against the San Francisco 49ers and ...

Though San Francisco 49ers QB Brock Purdy has made progress with his toe injury, he's been deemed "highly unlikely" to start.

www.si.com/nfl/49ers Why these injuries could swing the 49ers' Week 2 matchup vs. Arizona East Grays Harbor Fire and Rescue ...

The San Francisco 49ers face the Arizona Cardinals on Sunday, Sept. 21, 2025 in Week 3 of the NFL season at State Farm ...

Brock Purdy missed the 49ers' win at the Saints on Sept. 14. The Arizona high school football standout could return vs. the ...

San Francisco 49ers quarterback Brock Purdy returned to practice on Wednesday after missing a game with a toe injury.