The Sunday afternoon Cardinals vs. 49ers game will kick off at 4:25 p.m. ET on FOX. (Out-of-market fans can catch the game on ...

The San Francisco 49ers (2-0) host an NFC West showdown against the Arizona Cardinals (2-0) on Sunday, September 21, 2025 at ...

The Arizona Cardinals and San Francisco 49ers meet in Week 3 of the NFL season Sunday afternoon at Levi's Stadium.

Mac Jones is expected to again start in place of Brock Purdy as the 49ers host the Arizona Cardinals on Sunday.

Coach Kyle Shanahan said Friday that if 49ers wanted Purdy to be suited up as the emergency No. 3 quarterback, then Martinez, ...

The San Francisco 49ers face the Arizona Cardinals on Sunday, Sept. 21, 2025 in Week 3 of the NFL season at State Farm ...

They announced Saturday that they elevated quarterback Adrian Martinez and receiver Malik Turner from the practice squad.

Learn which TV channel or how to live stream the NFL Week 3 San Francisco 49ers and Arizona Cardinals game, Sunday, Sept. 21.

San Francisco is a 2.5-point favorite in the latest Cardinals vs. 49ers odds from SportsLine consensus, while the over/under ...

The Arizona Cardinals made their two standard practice squad elevations ahead of Week 3's road test against the San Francisco ...

Starting Monday, Gilman Playground, Laurelhurst Playfield, and Mount Baker Park will be open from 7 a.m. to 10 p.m. on ...

Date: Sunday, Sept. 21 | Time: 4:25 p.m. ET Location: Levi's Stadium -- Santa Clara, California TV: Fox | Stream: NFL + Follow: CBS Sports App Odds: 49ers -3; O/U 43.5 (via DraftKings) ...