Mac Jones is expected to again start in place of Brock Purdy as the 49ers host the Arizona Cardinals on Sunday.

Arizona comes into this game 2-0, but as a more flawed team than the one that swept San Francisco last year. The Cardinals' running game has not gotten untracke ...

Coach Kyle Shanahan said Friday that if 49ers wanted Purdy to be suited up as the emergency No. 3 quarterback, then Martinez, ...

San Francisco coach Kyle Shanahan said it’s “ highly unlikely ” Brock Purdy would return as the 49ers’ starting quarterback on Sunday, which means it’s highly likely Mac Jones will be under center for ...

The San Francisco 49ers and Arizona Cardinals will meet on Sunday. Here's what fantasy owners should do with their 49ers in ...

The Seattle Seahawks fanbase can sit back and laugh as the rival 49ers struggle with another QB controversy brewing.

The San Francisco 49ers seemed to lose all hopes of securing definitive wins this season when quarterback Brock Purdy suffered a turf toe injury. Despite the initial expectation being for him to be ...

Date: Sunday, Sept. 21 | Time: 4:25 p.m. ET Location: Levi's Stadium -- Santa Clara, California TV: Fox | Stream: NFL + Follow: CBS Sports App Odds: 49ers -3; O/U 43.5 (via DraftKings) ...

Having said that, Mariota did come in in relief for Daniels on three occasions last season, throwing for 364 yards and four touchdowns while also adding a score on the ground. The Commanders could ...

The 49ers host the Cardinals in Week 3 on Sunday, September 21, 2025. With Brock Purdy unlikely to play, Mac Jones gets the start as San Francisco enters as a slight favorite. See odds, predictions, ...

The 49ers elevated quarterback Adrian Martinez from the practice squad for Sunday's game against the Cardinals, the team ...

San Francisco is a 2.5-point favorite in the latest Cardinals vs. 49ers odds from SportsLine consensus, while the over/under ...