Pancreatic cancer has a significantly poor prognosis; therefore, the development of effective treatments is an unmet clinical need. The major drawback in this field was the lack of useful model ...

This new method, called REVeRT (reconstitution via mRNA trans-splicing), also uses the principle of dual AAV vectors. However, unlike previous technologies, it relies on the assembly of split gene ...

These mutations improve biocontainment, transformation stability, and overall performance in genetic engineering of plants. Complementing the strains, researchers also developed new plasmids and a ...

However, traditional gene delivery methods, such as Agrobacterium-mediated transformation and gene guns, are often slow, inefficient, and can damage plant tissues. These highlight the need for more ...

A novel method of gene therapy is helping children born with a rare genetic disorder called AADC deficiency that causes severe physical and developmental disabilities. The study, led by researchers at ...

Accidental discoveries have always led to intriguing research in science, and one such incident by a group of researchers has been published in the journal American Chemical Society. Image Credit: ...

Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a ...

This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...

As a way of treating hemophilia, Japanese researchers have, for the first time, delivered gene therapy directly into the livers of baboons without using a viral carrier. The study’s results indicate ...

Gene therapy is a revolutionary approach to treating genetic disorders by introducing functional genes into cells to replace or correct defective genes. It involves the use of genetic material, such ...