An organoid-based screening platform that allows one-gene-at-a-time knockdown across a whole tissue has been used to identify the genes that regulate closure of the neural tube in humans.

In the cancer type multiple myeloma, the malignant cells differ significantly from normal cells regarding the layer of chemical “tags” on DNA and proteins that control whether genes are turned on or ...

Brian Cunniff, an assistant professor of pathology and laboratory medicine at the University of Vermont, will discuss how the subcellular positioning of mitochondria regulates gene-expression patterns ...

Sex-biased gene expression in the body organs evolves rapidly, supporting a mosaic model of maleness and femaleness across tissues and thus challenging binary views of sex characteristics in mammals.