The Arizona Cardinals and San Francisco 49ers meet in Week 3 of the NFL season Sunday afternoon at Levi's Stadium.

The Sunday afternoon Cardinals vs. 49ers game will kick off at 4:25 p.m. ET on FOX. (Out-of-market fans can catch the game on ...

The San Francisco 49ers face the Arizona Cardinals on Sunday, Sept. 21, 2025 in Week 3 of the NFL season at State Farm ...

The San Francisco 49ers (2-0) host an NFC West showdown against the Arizona Cardinals (2-0) on Sunday, September 21, 2025 at ...

The New Orleans Saints are set to take on the Seattle Seahawks in Week 3, here is how and where you can watch the upcoming matchup.

They announced Saturday that they elevated quarterback Adrian Martinez and receiver Malik Turner from the practice squad.

Learn which TV channel or how to live stream the NFL Week 3 San Francisco 49ers and Arizona Cardinals game, Sunday, Sept. 21.

Mac Jones is expected to again start in place of Brock Purdy as the 49ers host the Arizona Cardinals on Sunday.

Preview the Week 3 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, betting lines and more.

Coach Kyle Shanahan said Friday that if 49ers wanted Purdy to be suited up as the emergency No. 3 quarterback, then Martinez, ...

Arizona comes into this game 2-0, but as a more flawed team than the one that swept San Francisco last year. The Cardinals' ...