Mac Jones is expected to again start in place of Brock Purdy as the 49ers host the Arizona Cardinals on Sunday.

Coach Kyle Shanahan said Friday that if 49ers wanted Purdy to be suited up as the emergency No. 3 quarterback, then Martinez, ...

The Arizona Cardinals have a chance at a 3-0 start when they head to San Francisco to take on the 49ers. It's their toughest ...

The Arizona Cardinals completed their week of practice on Friday for Sunday’s game against the San Francisco 49ers and ...

Though San Francisco 49ers QB Brock Purdy has made progress with his toe injury, he's been deemed "highly unlikely" to start.

The Arizona Cardinals dominated on the ground in 2024, finishing second in yards per carry. 2025 has been more of a struggle ...

San Francisco 49ers quarterback Brock Purdy returned to practice on Wednesday after missing a game with a toe injury.

The San Francisco 49ers have been leaning on Christian McCaffrey early in the season. The star running back has 17.5 rushes per game through two weeks and has added 8.5 targets per game. His total of ...

When Kyler Murray is at his best, he can be a nightmare for the opposition with his ability to break off long runs, avoid sacks and extend plays doing damage to even the best NFL defenses.

Here is everything you need to know about the San Francisco 49ers vs. Arizona Cardinals, including TV and streaming options for the Week 2 NFL game.

USA Today's NFL experts make their picks for a Week 3 showdown between the San Francisco 49ers and Arizona Cardinals ...

The San Francisco 49ers could have a huge leg up in the division with a win over the 2-0 Arizona Cardinals in Week 3. While Arizona did not beat world beaters in their two games, they do have two wins ...