Mac Jones is expected to again start in place of Brock Purdy as the 49ers host the Arizona Cardinals on Sunday.

Coach Kyle Shanahan said Friday that if 49ers wanted Purdy to be suited up as the emergency No. 3 quarterback, then Martinez, ...

They announced Saturday that they elevated quarterback Adrian Martinez and receiver Malik Turner from the practice squad.

San Francisco is a 2.5-point favorite in the latest Cardinals vs. 49ers odds from SportsLine consensus, while the over/under ...

The Arizona Cardinals take on the San Francisco 49ers Sunday in Week 3, kicking off at 4:25 p.m. ET (1:25 p.m. Arizona time) from Levi's Stadium in Santa Clara. It is the first of two matchups between ...

It's a big week for the Arizona Cardinals and quarterback Kyler Murray. Murray, who will look to guide Arizona to a 3-0 start to the season, are roa ...

Learn which TV channel or how to live stream the NFL Week 3 San Francisco 49ers and Arizona Cardinals game, Sunday, Sept. 21.

The Arizona Cardinals made their two standard practice squad elevations ahead of Week 3's road test against the San Francisco ...

Here is everything you need to know about the San Francisco 49ers vs. Arizona Cardinals, including TV and streaming options for the Week 2 NFL game.

The San Francisco 49ers battle the Arizona Cardinals in their home opener at Levi’s Stadium on Sunday, Sept. 21 at 1:25 p.m.

Date: Sunday, Sept. 21 | Time: 4:25 p.m. ET Location: Levi's Stadium -- Santa Clara, California TV: Fox | Stream: NFL + Follow: CBS Sports App Odds: 49ers -3; O/U 43.5 (via DraftKings) ...

Murray shined last season against the 49ers, starting on his second snap when he raced 50 yards for a touchdown and not ...