The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...

The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

Selpercatinib in RET Fusion–Positive Non–Small Cell Lung Cancer: Final Safety and Efficacy, Including Overall Survival, From the LIBRETTO-001 Phase I/II Trial 3'RNA sequencing was performed in 1,733 ...

Incorporating Continuous Mammographic Density Into the BOADICEA Breast Cancer Risk Prediction Model Cell-free DNA (cfDNA) and matched tumor sample from patients with BTC were analyzed using targeted ...

PSAT1 and PSRC1 are upregulated in SCLC, with PSRC1 linked to lower survival rates, suggesting potential therapeutic targets. COLEC12, PLLP, and HP are downregulated, affecting immune response and ...

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer. While indispensable for embryonic patterning ...

Research shows polystyrene nanoplastics accelerate ovarian cancer growth by activating CDK4/6 pathways, with Palbociclib ...

Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat ...