The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...
Selpercatinib in RET Fusion–Positive Non–Small Cell Lung Cancer: Final Safety and Efficacy, Including Overall Survival, From the LIBRETTO-001 Phase I/II Trial 3'RNA sequencing was performed in 1,733 ...
The G2 checkpoint ensures that DNA replication is complete and that any DNA damage that occurred during S phase has been ...
The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...
The field of cancer immunology and immunotherapy is witnessing rapid advances as researchers strive to overcome persistent challenges related to immune ...
Mitochondria, the “powerhouses of the cell,” are vital cellular organelles that govern energy metabolism, maintain redox ...
PSAT1 and PSRC1 are upregulated in SCLC, with PSRC1 linked to lower survival rates, suggesting potential therapeutic targets. COLEC12, PLLP, and HP are downregulated, affecting immune response and ...
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Enhancing the cancer-immunity cycle through innovative vaccines
Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat ...
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