Ubiquitin controls the lifespan and distribution of proteins in the cell, but it can also determine their shape, function, or interactions with other cellular components. Ubiquitin ligases are key to ...

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing α-synuclein and ubiquitin. Rare ...

Researchers from Harvard Medical School (HMS) have discovered how a protein called midnolin plays a key role in degrading many short-lived nuclear proteins. Their study showed that midnolin acts by ...

Mechanisms associated with the genesis of cancer stem cell stemness, such as oxidative stress, tumor metastasis and recurrence, hypoxia induction, and tumor invasion. Genes & Diseases publishes ...

Although most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals experience mild symptoms, some contract a severe infection that affects multiple organs in the acute ...

SE-GAP-ResNet: A machine learning model for abnormal breast detection. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a full text component.

All multicellular organisms keep a balance between sink and source activities by controlling nutrient transport at strategic positions. In most plants, photosynthetically produced sucrose is the ...