Life begins with a tiny orchestra of stem cells, setting the stage for the body’s grand symphony of development. As the performance unfolds, a dynamic interplay of factors takes center stage, ...
UCSF researchers identified 30 transcription factors that reverse age-related gene expression in fibroblasts. Using CRISPR to adjust these regulators restored youthful metabolism and growth in old ...
Peer-reviewed discovery platform and data in PNAS show that single transcription factor modulation reverses aging-associated gene expression and restores healthy cellular and tissue function in models ...
BOSTON, Jan. 28, 2026 (GLOBE NEWSWIRE) -- Life Biosciences, Inc., (“Life Bio”) a biotechnology company pioneering cellular rejuvenation therapies to reverse and prevent multiple diseases of aging, ...
Jonas Salk quietly built the polio vaccine through rigorous, methodical work in Pittsburgh: treating patients, refining data, conducting massive trials, before unveiling results that altered the ...
Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells. Scientists ...
A team led by researchers has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other ...
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