New research published in The Journal of Immunology suggests that a lack of dietary iron can negatively affect the ability of ...

Researchers found a hidden signal that makes T cells shut down during cancer fights. Turning off this signal reawakens the cells and helps them attack tumors more effectively.

There are many kinds of T cells, and they play different parts in defending the body. Some T cells kill infected cells, ...

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the setting ...

Memory T cells are a special type of white blood cell that "remember" past infections and vaccines, helping our bodies to ...

Researchers investigating ways to reduce exhaustion in cancer-fighting T-cells found that the Golgi apparatus can be used as a simple marker -- more Golgi means a more robust cell. The Golgi apparatus ...

An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve immunotherapy. Courtney and his team sought to exploit this property of TIP to ...

Ohio State researchers have discovered that exhausted T cells collapse under the weight of misfolded proteins, activating a destructive stress response called TexPSR. Unlike normal stress systems, ...

Tumors trigger T-cell exhaustion through a TSP-1–CD47 signaling pathway. Blocking it can restore immune strength and improve cancer treatment.

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...