Nibbler (Nbr) is a 3′-to-5′ exoribonuclease whose catalytic 3′-end trimming activity impacts microRNA (miRNA) and PIWI-interacting RNA (piRNA) biogenesis. Here, we report on structural and functional ...
Victor Ambros receives funding from the U.S. National Institutes of Health. The Conversation Weekly podcast caught up with Victor Ambros from his lab at the UMass Chan Medical School to learn more ...
Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix. These proteins are composed of glycosaminoglycan chains that are covalently attached to a ...
The prize was awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA, which helps determine how cells develop and function. By Teddy Rosenbluth and Derrick Bryson Taylor Victor ...
Levels of molecules associated with genetic function, such as microRNA, can be an important indicator of abnormal activity associated with cancer. However, little is known about how different ...
The capsid of the hepatitis B virus has a very unique structure. It is composed of many monomers which interact to provide flexibility to its structure and function. Hepatitis B virus (HBV) is a ...
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