Some single-celled organisms are known to transition to multicellularity during their lifetimes, usually either by cloning themselves or when many similar cells come together to form a larger ...

Animals, from worms and sponges to jellyfish and whales, contain anywhere from a few thousand to tens of trillions of nearly genetically identical cells. Depending on the organism, these cells arrange ...

Single-cell omics is a transformative area within life sciences, enabling researchers to untangle cellular heterogeneity, uncover developmental lineages, ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

This review, led by a team of prominent researchers from Zhejiang University (Guoji Guo, Hongshan Guo, Yijun Ruan, Yongcheng Wang), Peking University (Zemin Zhang, Dong Xing), and BGI Research (Xun Xu ...

Researchers have combined two sequencing technologies in single cells to find new differences in mRNAs resulting from Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease. Diseases ...

Antibody therapeutics are a dominating feature of the current drug development landscape, but increasing costs and time-consuming workflows represent major barriers to their discovery and development.