SARS-CoV-2 recombination arises when RNA-dependent RNA polymerase switches templates during genome replication in cells co-infected by distinct viral lineages. This process can shuffle mutations ...

Viruses are masters of stealth. From the moment a virus enters the host's body, it begins hijacking its cells. First, the virus binds to a specific protein on the cell's surface through a lock-and-key ...

The emergence of SARS-CoV-2 has spurred extensive investigation into the molecular underpinnings of viral entry, replication and pathogenesis. Central to host invasion is the spike glycoprotein, whose ...

As scientists, we often think we understand a virus—its structure, its tricks, the way it moves through the body. But every once in a while, we stumble upon something unexpected—something that ...

Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), understanding the mechanisms underlying severe pneumonia has remained a major research challenge. Although mouse ...

This is a preview. Log in through your library . Abstract Type VI CRISPR-Cas systems have been repurposed for various applications such as gene knockdown, viral interference, and diagnostics. However, ...

The project is led by Professor Wang Guoqing of the School of Basic Medicine and Professor Qiu Jiazhang of the School of Veterinary Medicine of Jilin University. In this study, they performed ...