When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits ...

Scientists have created a model to study the role of RNA splicing defects in Alzheimer's disease, revealing degeneration and toxicity caused by neuron hyperexcitability. Researchers have puzzled over ...

A new study has revealed how a natural compound in our cells can reverse brain deficits in animal models of Alzheimer’s disease. The research shows that boosting levels of a molecule called NAD+ ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

A new study shows that RNA splicing, not just gene expression, holds powerful clues to why some mammals live far longer than ...

A collaborative study by scientists at the University of California, Riverside, and University of Southern California reports ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function ...

In a recent preprint* uploaded to the bioRxiv server, researchers developed and trained a foundational model to predict tissue-specific RNA expression, splicing, RNA binding protein specificity, and ...

Researchers have puzzled over the neurodegenerative disorder Alzheimer's disease for decades, but treatments to stop or reverse the disease's effects on the brain have remained elusive. Scientists at ...