Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 15 (Jul. 22, 2003), pp. 8692-8697 (6 pages) The DnaA replication initiation protein has been shown to be ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, No. 14 (Jul. 15, 1987), pp. 4781-4785 (5 pages) RepA, an initiation protein of R1 plasmid replication, was ...

Toxin-antitoxin (TA) systems are now known to negatively control plasmid replication. Toxin-antitoxin (TA) systems are now known to negatively control plasmid replication, according to Thomas Wood, ...

Plasmids, small circular DNA molecules found in bacteria, may contain antibiotic-resistance genes and have the ability to replicate independently. Bacteria can transfer these plasmids to one another, ...

A collaboration of researchers from Harvard Medical School and the University of Virginia, led by Dr. Anindya Dutta, has created an artificial mammalian origin of replication that will facilitate the ...

Astrivax BV has raised €30 million (US$30.1 million) in a seed round to take forward the development of a novel vaccine technology that combines a plasmid vector with a replication-competent virus.

Adeno-associated virus (AAV) vectors play a pivotal role in gene therapy, delivering therapeutic genes with high precision and safety. However, a significant challenge in the biomanufacturing of these ...

SAN FRANCISCO & COLUMBUS, Ohio--(BUSINESS WIRE)--Ray Therapeutics, a biotechnology company developing optogenetic gene therapies for patients with retinal degenerative conditions, and Forge Biologics, ...

Nucleic acid purification procedures have enjoyed a long history, beginning with the first isolation of "nuclein" in 1869 by Freidrich Meischer. In 1958, Matthew Meselson and Frank Stahl demonstrated ...

Bionova Scientific, a full-service biologics contract development and manufacturing organization (CDMO) and subsidiary of global conglomerate Asahi Kasei, has announced the opening of a 10,000 ...