Formation of the RNA polymerase II (Pol II) open complex (OC) requires DNA unwinding mediated by the transcription factor TFIIH helicase-related subunit XPB/Ssl2. Because XPB/Ssl2 binds DNA downstream ...

A research group led by the University of Bologna identified a new mechanism that allows to obtain serological tests that are quicker, more cost-effective and more reliable than those currently in use ...

Human-rodent hybrid cell lines have been analyzed with regard to their human DNA content by using various DNA probe sets, derived from the hybrids, for in situ hybridization to normal human metaphase ...

Molecular mechanism of transformation from adenocarcinoma to small-cell lung cancer after EGFR-TKI. A phase 1b study of famitinib plus docetaxel as 2nd line setting in patients with metastatic ...

A new, less error-prone approach to sequencing Sars-CoV-2 genomes has revealed key information on factors responsible for the development of new COVID-19 variants. Researchers at Baylor College of ...