Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolves rapidly under the pressure of host immunity, as evidenced by waves of emerging variants despite effective vaccinations, ...

Nucleotides are the fundamental units that make up the genetic material of all living organisms. They are the building blocks of DNA and RNA, which store and transmit genetic information. Nucleotides ...

Oligonucleotides are short strands of DNA or RNA that scientists use to influence biological processes at the genetic level.

A new paper published in Nature Biotechnology this week titled, “Template-independent enzymatic synthesis of RNA oligonucleotides,” provides details of a method for synthesizing single-stranded RNA ...

An organic sulfur compound known as a thioester spontaneously catalyzing the binding of RNA to amino acids may be where it ...

RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste.

A straightforward and reproducible synthesis pathway for a diverse range of ATP- and ADP-coupled biomolecules has been developed by modifying an established reagent. Researchers at the Institute for ...

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...