Barcelona, 10 October 2024 - DNA—the molecule that carries the genetic information of all living organisms—is packaged within cells in a complex manner that allows it to function efficiently.

Nucleosome Remodeling Factor (NURF) is an ATP-dependent nucleosome remodeling complex that alters chromatin structure by catalyzing nucleosome sliding, thereby exposing DNA sequences previously ...

We have measured the effect of the histones in the nucleosome core particle on methylation of purines in nucleosome DNA by dimethyl sulfate. By using 32P terminally labeled nucleosome cores, we have ...

Histones serve as slates to a dizzying array of modifications, but researchers are confident they can decipher the epigenetic puzzle. Roughly two meters of DNA gets packed into every cell nucleus in ...