How major nuclear protein complexes control specialized gene regulation in cancer and beyond

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
GEN

Input Determines Output: Building a Protein Expression Platform

Making proteins for research or therapies often starts with cell-line development. In many applications, genetic engineering is used to optimize a cell line for producing high levels of the intended ...
BioWorld

RNA-targeting CRISPR-Cas13 and engineered U1 correct variants in Stargardt disease

Disruption of alternative splicing can generate abnormal mRNA variants, producing nonfunctional proteins or triggering ...
News Medical

Rapid protein expression: DNA to assay-ready proteins in 48 hours

This article is based on a poster originally authored by Sunidhi Shetty, Narasimha Murthy Bandaru, Anna Moberg and Marco Manni, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...