Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division.

Using sequencing techniques, researchers associated 51 mutations in mitochondrial DNA with amyotrophic lateral sclerosis (ALS), an incurable degenerative neurological disorder that leads to muscle ...

Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...

Earlier this week, a team of researchers announced that they’d made a discovery about how we inherit mitochondrial dna from ...

Mitochondrial DNA (MtDNA) is a circular DNA molecule that is essential for mitochondrial function and, unlike the nuclear genome, is present in multiple copies in most cells. MtDNA has been thought to ...

Researchers introduced a yeast enzyme, ScURA, into human cells, enabling nucleotide synthesis independent of mitochondrial ...

Nucleotide synthesis—the production of the basic components of DNA and RNA—is essential for cell growth and division. In most ...

Researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited. The team identified two enzymes that regulate a chemical modification, 6mA, in mitochondrial ...

In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...

The tiny little powerhouses of our cells: mitochondria, are unique among organelles because they carry their own tiny little genomes. This genetic material is separate from the rest of our genomic DNA ...