One problem in gene therapy is that not all genes transfer equally well into the target cells. Researchers have now developed a flexible method to transfer large genes efficiently and without ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

Both prokaryotic and eukaryotic organisms have developed genetic mechanisms by which they can evolve to adapt to and meet the challenges thrown at them by a changing environment. One process by which ...

The AAV carrier substances have an advantageous safety profile and high gene transfer efficiency, meaning they are often used in gene therapies and in gene editing with CRISPR/Cas. But, AAVs have ...

Pancreatic cancer has a significantly poor prognosis; therefore, the development of effective treatments is an unmet clinical need. The major drawback in this field was the lack of useful model ...