Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

The liver is an extraordinary organ. It detoxifies the body every day without needing a cleanse, a tea or a reset.

Steatotic liver disease (commonly called fatty liver disease) progresses silently. Even in the absence of noticeable symptoms, changes begin to unfold inside the liver. While hepatic fat accumulation ...

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks ...

The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called ...

Resection of liver metastases is considered the only treatment with curative potential for patients with metastatic colorectal cancer to the liver (CRLM). However, only a minority of patients with ...

Discover how a miniature model of the human liver can help improve toxicology testing for food contaminants, reducing the ...