After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, ...
Researchers at the University of Twente and Radboudumc are developing a promising new model to enhance understanding of the ...
The new molecules selectively reduced inflammatory signaling in human immune cells without affecting other immune pathways. Treatment with the molecules also reduced inflammation in mice with the ...
Modern lifestyle factors such as circadian disruption, sleep deprivation, stress, and exercise reshape the gut bacteriome and ...
Researchers have identified a key molecular interaction that accelerates Parkinson’s disease by damaging the brain’s energy ...
Alzheimer's disease has long been thought to be irreversible, but new research using a mouse model offers hope.
For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery. Despite billions of dollars ...
Researchers at UCL and Great Ormond Street Hospital (GOSH) have developed the first-ever lab-grown mini-stomach that contains ...
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Replacing large mouse gene regions with human DNA
Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...
Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...
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