The most effective way of determining protein structure from sequence alone is by using computational methods. This is based on direct comparison of the unknown protein sequence with the sequence of a ...

Sequencing the first human genome was a herculean effort that took 13 years, hundreds of researchers around the globe and billions of dollars. But recent advances in technology have transformed genome ...

The traditionally held hypothesis about the highly ordered organization of DNA describes the interaction of various proteins with DNA sequences to mediate the dynamic structure of the molecule.

Structural genomics projects aim to solve the experimental structures of all possible protein folds. Such projects entail a conceptual shift from traditional structural biology in which structural ...

'Inheritance through homology' is the most common and generally more accessible approach to function prediction, but orthology should be established where possible to improve confidence in predictions ...