Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

Researchers at the University of Bath have discovered how DNA damage caused by a faulty DNA protection and repair system can ...

New research shows rapamycin’s powers go beyond slowing cell growth. It appears to shield DNA itself from damage. Since DNA ...

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

Organisms like eukaryotes and prokaryotes have sophisticated mechanisms of DNA repair after damage. Failure of repairing the DNA damage is considered to be the cause of induction of cell death, ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Research from scientists at Albert Einstein College of Medicine, Northwestern University, and elsewhere indicates that forming long-term memories requires DNA damage and brain inflammation. The ...

Normal metabolic activity produces reactive oxygen species (ROS) that, if not eliminated, can damage cellular components. As a result, ROS from overactive mitochondria are frequently cited as a source ...