There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called ...

This new review article highlights the pivotal and paradoxical role of R-loops in maintaining genomic stability while simultaneously posing risks to it. These three-stranded nucleic acid structures, ...

This study is achieved by Professor Wei Xu’s research team from Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences. The research team established mDRIP-seq, a ...

A schematic showing how R-loops, a hybrid of RNA and DNA, can form during DNA transcription when the messenger RNA chain being assembled by the RNA polymerase binds to one of the DNA strands. R-loops ...