Researchers have identified a gut-genetic interaction that could trigger an overactive immune response in the colon — offering one possible explanation for the pain and bleeding of ulcerative colitis, ...

Harvard immunologist Dennis Kasper and his colleagues have found that tiny changes in gut bacteria can flip the immune system from calm to inflamed, even when the microbes look harmless. Their work, ...

Microspheres that sense gastrointestinal disease are suspended in solution (L), and then attracted to the side of a test tube by a magnet (R) so researchers can easily retrieve them from biological ...

The study which compared MB310, a precision microbiome medicine, with placebo in 29 ulcerative colitis (UC) patients met its primary and ...

A toxin produced by bacteria found in dirty water kills off immune cells in the lining of the colon, meaning people whose guts are colonised by these bacteria are much more likely to develop a ...

Diagram showing the mechanism discovered in the study. Inflammation of the intestines in ulcerative colitis results from an excessive helper Th2 immune response. Smoking leads to aromatic compounds ...

Bacteria uses multiple defense mechanisms to survive in the host body. Shigella bacteria, that causes colitis, disable multiple host defense pathways using three specialized effector proteins, as ...

Move over, colonoscopies — researchers report in ACS Sensors that they’ve developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal ...

Smoking's not often touted for its health benefits. But it's been known to help those suffering from colitis even though it exacerbates Crohn's disease. New research that could help treat the ...

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. Disruption of the interaction between the gut microbiome and the host can contribute to ...

What if creeping fat in Crohn’s disease isn’t collateral damage, but rather the body’s attempt to trap microbiota escaping ...