By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining ...

A study conducted by researchers at Ohio State University and the New York University Grossman School of Medicine in the USA, has revealed that optimization of codon for bacterial expression causes ...

Gene sequences are made up of nucleotide bases, which are 'read' by the cell's machinery in triplets; three nucleotide bases are interpreted as one codon, and every codon has a corresponding amino ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

Alltrna is advancing a new class of genetic medicines based on the power of tRNA biology to universally treat Stop Codon Disease, which encompasses thousands of genetic diseases caused by a premature ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...